Wednesday, February 22, 2012

Proteolysis: protein


Lactic acid bacteria have the property of producing lactic acid from sugar process is called fermentation. Rod >> << Bacillus, Leuconostoc, Pediococcus and Streptococcus



important members of this group. Taxonomy of lactic acid bacteria was found in gram >> << reaction and the formation of lactic acid fermentation of various carbohydrates. Lactobacilli are Gram-positive and differ in morphology with long slender rods to short >> << kokkobatsill, often forming chains. Their metabolism is enzymatic, and some >> << are aerotolerant and can use oxygen through enzyme flavoproteidov, while others


strictly anaerobic. While the dispute bearings


coagulans Bacillus are facultative anaerobes


other strictly anaerobic. Growth is optimal at pH 5. 05.05. 8 >> << organisms have complex nutritional requirements for amino acids, peptides, nucleotides,


vitamins, minerals, fatty acids and carbohydrates. Reid


divided into three groups depending on the fermentation model: 1. homofermentative >> <<: produces more than 85% lactic acid from glucose. 2. heterofermentatyvnyh: do only 50% lactic acid and a large number of ethanol


acetic acid and carbon dioxide. 3. Less is known


heterofermentatyvnyh species that produce DL-lactic acid, acetic acid and carbon dioxide. Species


are therapeutically used: L. sporogenes



acidophilic L. L. Plantarum


L. casei


L. Brevis


L. delbruckii


L. Lactis



metabolic activity of lactobacilli are responsible for their therapeutic effect. Lactobacilli


cultured in milk medium, follow these steps: 1. Proteolysis: Protein



broken easily digestible components. These actions of lactobacilli in >> << gastrointestinal protein to the host gets easily absorbed, the object >> << important for children, convalescents and geriatric nutrition. 2. Lypolyz:



complex fat broken down into easily digestible components. This purchase strattera property


useful in the preparation of dietetic products for children, geriatrics and convalescents ..


Lactobacilli also assist in the deconjugation of bile salts


. Both of these findings have clinical significance. 3. Lactose metabolism:



Lactic acid bacteria have enzymes b-galactosidase, glycolases and lactate dehydrogenase (LDH)


, which produce lactic acid from lactose. Lactic acid is said to have some physiological advantages



, such as: a) increasing the digestibility of milk proteins


through deposition of particles in cheese. b) improving the use


calcium, phosphorus and iron. c) Incentive >> << secretion of gastric juice d) accelerate forward


e contents of the stomach) to perform functions


energy in the process of respiration. The levels of optical isomeric forms


lactic acid produced depends on the nature of culture. Structural


configuration of these isomers as follows:


D (-) levogyrate


lactic acid L (+) lactic acid pravovraschayuschym >> << The people, both isomer


is absorbed from the gastrointestinal tract. While L (+) lactic acid and completely


rapidly metabolized in the synthesis of glycogen, D (-) lactic acid is metabolized at a lower speed >> << and unmetabolized acid excreted in the urine. The presence of unmetabolized


lactic acid leads to metabolic acidosis in children. L. acidophilic


produces


D (-) - form and, therefore, controversial clinical benefits, although it was previously


probiotic of choice in various therapeutic drugs. L. sporogenes



on the other hand produces only L (+) - lactic acid and thus is the best. The ability of lactobacilli >> << convert lactose into lactic acid used in the successful treatment of lactose intolerance


. People who suffer from this condition can not digest lactose because of the lack


or violation of essential enzyme systems. Lactic acid, lowering pH of intestinal environment


4 to 5, inhibits the growth of putrefactive microorganisms and


E.coli, which require a more optimal pH of 6 to 7. Some of the volatile acids formed


in the process of fermentation also have some antimicrobial activity in low


redox potential. Production bactericins: bacteriocins proteins or protein complexes with bactericidal activities directed against


species closely related to the producer bacterium. Inhibitory activity of L.


sporogenes



and lactobacilli on putrefactive bacteria is believed to be partly due


Manufacturing bacteriocins. Some >> << bactericins isolated from lactobacilli are presented in Table 2. 1:


Table 2. 1:


bacteriocins isolated from various species of Lactobacillus. Manufacture of other antagonistic substances >> <<: >> << Lactic acid bacteria also inhibit the growth of harmful putrefactive microorganisms through other >> << metabolic products such as hydrogen peroxide, carbon dioxide and diacetyl. Metabolites


lactic acid bacteria, providing antagonistic action against putrefactive microorganisms


and their actions are listed in Table. 2. 2:


Table 2. 2:


antagonistic activity of lactic acid bacteria due to the synthesis of vitamins



Experiments on dairy products have shown that lactic cultures require vitamins for th


metabolic activity. However, in some cultures, milk synthesize vitamins


16. Friend


al. Reported that B-vitamin composition of milk products


is a function of species and strain of lactic acid bacteria used in their production >>. << In addition, vitamins are synthesized in the mammary cultures >> << intestinal microflora in symbiosis with other flora. It was


noted that host diet influences the nature and levels of beneficial intestinal microflora


such as lactobacilli. Availability of food >> << fruktoolihosaharidy found increasing effects of healthy intestinal bacteria of lactic acid >> <<. These compounds in nature is found in foods such as onions, edible burdock and


wheat, which are being used as a non-nutritive sweeteners (Neosugar, Meiologo). They


have the advantage of being indigestible by humans and animals, making her


valuable dietary products. They, however, selectively used >> << intestinal lactic acid bacteria, especially bifidobacteria, thereby increasing the effect of healthy


these useful intestinal flora. .


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